Antidiabetic agent 6
Product Specifications
UNSPSC Description
Antidiabetic agent 6 (Compound 19) is an antidiabetic Agent. Antidiabetic agent 6 stimulates GLUT4 translocation by activation of the PI3K/AKT-dependent signaling pathway. Antidiabetic agent 6 reduces blood glucose levels in Streptozotocin (HY-13753)-induced diabetic rats[1].
Target Antigen
Akt; GLUT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/antidiabetic-agent-6.html
Smiles
O=C1C2=C(CC(C)(C1)C)NC(C)=C(C2C3=CC=C(C(Cl)=C3)Cl)C(NCCC4=CNC5=C4C=CC=C5)=O
Molecular Weight
522.47
References & Citations
[1]Katiyar S, et al. Design, Synthesis, and Biological Evaluation of 1,4-Dihydropyridine-Indole as a Potential Antidiabetic Agent via GLUT4 Translocation Stimulation. J Med Chem. 2024 Jul 25;67(14):11957-11974.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163853/Antidiabetic-agent-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163853/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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