Metrizamide

Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations[1]. Metrizamide inhibits human brain hexokinase[2].

Product Specifications

CAS Number

[31112-62-6]

Product Name Alternative

Amipaque

UNSPSC

12352005

Target

Hexokinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/metrizamide.html

Purity

99.0

Solubility

DMSO : ≥ 50 mg/mL

Smiles

IC(C(N(C)C(C)=O)=C1I)=C(C(N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)OC2O)=O)C(I)=C1NC(C)=O

Molecular Formula

C18H22I3N3O8

Molecular Weight

789.10

References & Citations

[1]Vogelsang H, et al. Zerebrale und spinale Angiographie mit Metrizamid (Amipaque) [Cerebral and spinal angiography with metrizamide (amipaque) (author's transl) ]. Rofo. 1978;129 (5) :559-561. |[2]Bertoni JM. Metrizamide inhibits human brain hexokinase. Neurology. 1982;32 (8) :884-887. |[3]Funkquist B. Myelographic localization of spinal cord compression in dogs. A comparison between cisternal and lumbar injections of metrizamide "Amipaque" in diagnosing and locating spinal cord compression. Acta Vet Scand. 1975;16 (2) :269-287.