Oleyl anilide
Product Specifications
UNSPSC Description
Oleyl anilide (Oleic acid anilide) is a toxic agent found in some stocks of toxic oil, which is associated with toxic oil syndrome (TOS). Oleyl anilide is an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT) (IC50: 26 µM)[1][2].
Target Antigen
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/oleyl-anilide.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/C=C\CCCCCCCC(NC1=CC=CC=C1)=O
Molecular Weight
357.57
References & Citations
[1]Roth BD, et al. Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents. J Med Chem. 1992 May 1;35(9):1609-17.|[2]Cai P, et al. Immunotoxic response of oleic acid anilide and its hydrolysis products in female MRL (+/+) mice. J Immunotoxicol. 2005 Oct 1;2(4):231-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114619/Oleyl-anilide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114619/
Clinical Information
No Development Reported
CAS Number
5429-85-6
Curated Selection
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