Ac-ANW-AMC
Product Specifications
UNSPSC Description
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm)[1][2].
Target Antigen
Proteasome
Type
Dye Reagents
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac-anw-amc.html
Purity
99.40
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1OC2=CC=C(C=C2C(C)=C1)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C)NC(C)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O
Molecular Weight
588.61
References & Citations
[1]Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6:e27364, (2017). |[2]Sumin Kim, et al. Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates. Immune Netw. 2022 Apr 15;22(3):e28.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1705/Ac-ANW-AMC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1705/Ac-ANW-AMC-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2357123-49-8
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