H-Val-Val-OH

H-VAL-VAL-OH (Val-val) is a dipeptide in which two valine (Val) residues are linked by an amide bond. H-VAL-VAL-OH can be used for the synthesis of some important compounds such as Poststatin (HY-125432) [1][2][3].

Product Specifications

CAS Number

[3918-94-3]

Product Name Alternative

Val-Val

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-val-val-oh.html

Purity

99.0

Solubility

DMSO : 9.52 mg/mL (ultrasonic; adjust pH to 4 with 1M HCl) |H2O : 25 mg/mL (ultrasonic)

Smiles

CC(C)[C@@H](C(O)=O)NC([C@H](C(C)C)N)=O

Molecular Formula

C10H20N2O3

Molecular Weight

216.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Pierfrancesco Bravo, et al. Solution and solid-phase synthesis of trifluoromethyl peptides and mimetics. Journal of Fluorine Chemistry Volume 112, Issue 1, 28 November 2001, Pages 153-162.|[2]Pesenti C, et al. Total synthesis of a pepstatin analog incorporating two trifluoromethyl hydroxymethylene isosteres (Tfm-GABOB) and evaluation of Tfm-GABOB containing peptides as inhibitors of HIV-1 protease and MMP-9. Tetrahedron, 2001, 57 (30) : 6511-6522.|[3]Wasserman H H, et al. Application of acyl cyanophosphorane methodology to the synthesis of protease inhibitors: poststatin, eurystatin, phebestin, probestin and bestatin. Tetrahedron, 2003, 59 (35) : 6771-6784.