MM 07

MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.

Product Specifications

CAS Number

[1876450-21-3]

UNSPSC

12352209

Target

Apelin Receptor (APJ)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/MM_07.html

Purity

99.95

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C(CNC([C@H](CCCCN)NC([C@@H](NC([C@H]2NC([C@](NC([C@@H](NC([C@@]3([H])N(CCC3)C([C@@](CCCNC(N)=N)([H])NC([C@@H](N)CSSC2)=O)=O)=O)CCCNC(N)=N)=O)([H])CC(C)C)=O)=O)CC4=CN=CN4)=O)=O)=O)N[C@@H](CCSC)C(N5[C@@H](CCC5)C(N[C@H](C(O)=O)CC6=CC=CC=C6)=O)=O

Molecular Formula

C67H106N22O14S3

Molecular Weight

1539.89

References & Citations

[1]Brame AL, et al. Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension. 2015 Apr;65 (4) :834-40.