ABTL-0812
ABTL-0812 (α-Hydroxylinoleic acid) induces endoplasmic reticulum (ER) stress-mediated autophagy. ABTL-0812 is a first-in-class small molecule with anti-cancer activity[1].
Product Specifications
CAS Number
[57818-44-7]
Product Name Alternative
α-Hydroxylinoleic acid
UNSPSC
12352211
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/_alpha_-Hydroxylinoleic_acid.html
Purity
99.84
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
CCCCC/C=C\C/C=C\CCCCCCC(O)C(O)=O
Molecular Formula
C18H32O3
Molecular Weight
296.44
References & Citations
[1]Muñoz-Guardiola P, et al. The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells. Autophagy. 2020 May 13.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Available Sizes
Curated Selection
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