Effusol

Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline[1].

Product Specifications

CAS Number

[73166-28-6]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/effusol.html

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C=C3C=C

Molecular Formula

C17H16O2

Molecular Weight

252.31

References & Citations

[1]Kim, Ye Jin, et al. Antioxidant and Cytotoxic Activity of Compounds from the Stem of Juncus effuses. Journal of Applied Biological Chemistry. Volume 57 Issue 1 / Pages.47-51 / 2014 / 1976-0442 (pISSN) .|[2]Haruna Tamano, et al. CA1 LTP Attenuated by Corticosterone Is Canceled by Effusol via Rescuing Intracellular Zn 2+ Dysregulation. Cell Mol Neurobiol. 2019 Oct;39 (7) :975-983.