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Xanthurenic acid-d4

Product Specifications

UNSPSC Description

Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].

Target Antigen

Apoptosis; Endogenous Metabolite; mGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

99.09

Solubility

10 mM in DMSO

Smiles

OC1=C([2H])C([2H])=C([2H])C2=C1N=C(C(O)=O)C([2H])=C2O

Molecular Weight

209.19

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Copeland CS, et al. Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Badge

Hot

Clinical Information

No Development Reported

CAS Number

1329611-28-0

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