Resorcinolnaphthalein

Resorcinolnaphthalein is a specific angiotensin-converting enzyme 2 (ACE2) enhancer and activates ACE2 activity with an EC50 value of 19.5 μM. Resorcinolnaphthalein can be used for the investigation of hypertension and renal fibrosis[1].

Product Specifications

CAS Number

[41307-63-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/resorcinolnaphthalein.html

Concentration

10mM

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=CC=CC3=C2C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)O1)=CC=C3

Molecular Formula

C24H14O5

Molecular Weight

382.36

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Hernández Prada JA, et al.Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents.Hypertension. 2008 May;51 (5) :1312-7.