4'-Hydroxyvalerophenone
Product Specifications
UNSPSC Description
4'-Hydroxyvalerophenone (Compound 4) is an inhibitor of 17β-hydroxysteroid dehydrogenase (17β-HSD) with an IC50 of 60.52 μM[1].
Target Antigen
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-hydroxyvalerophenone.html
Solubility
10 mM in DMSO
Smiles
CCCCC(C1=CC=C(O)C=C1)=O
Molecular Weight
178.23
References & Citations
[1]Lota RK, et al. Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3). Bioorg Med Chem Lett. 2006 Sep 1;16(17):4519-22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W016604/4-Hydroxyvalerophenone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W016604/
Clinical Information
No Development Reported
CAS Number
2589-71-1
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