Anti-Calprotectin / MRP14 / S100A9 / Calgranulin B(rMAC3781)
Calprotectin is a heteroduplex of Protein S100-A8/A9 (also called MRP-8/14, or Calgranulin A/B). This antibody recognizes the 14 kDa B component (Protein S100-A9) of the complex. Protein S100-A9 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. Altered expression of this protein is associated with the disease cystic fibrosis. This antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Calprotectin; Protein S100-A9; Myeloid-related protein 14; MRP-14; Calgranulin B; CAGB; Calprotectin L1H Subunit
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
S100A8; S100A9
Gene ID
6279; 6280
NCBI Gene ID
416073; 112405
UniProt
P05109; P06702
Cellular Locus
Cytoplasmic|Cytoskeleton
Host
Mouse
Species Reactivity
Baboon,Cat,Cow,Dog,Goat,Guinea pig,Horse,Human,Monkey,Mouse,Pig,Rabbit,Rat
Immunogen
Affinity purified monocyte membrane preparation
Target Antigen
Calprotectin | S100-A9
Clonality
Recombinant Monoclonal
Isotype
IgG1 κ
Clone
rMAC3781
Conjugation
Purified, with BSA
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Field of Research
Immunology, Inflammation
Positive Control
Tonsil, lymph node, or spleen
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
12-14 kDa (doublet)
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7651600/datasheet/bnub3781-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7651600/msds/bnub3781-500.pdf
CAS Number
9007-83-4
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