Anti-Glycophorin A / CD235a (Erythrocyte Marker)(GYPA/3219R), CF405S conjugate
Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
GYPA
Gene ID
2993 & 2994
NCBI Gene ID
434973; 654368
UniProt
P02724
Cellular Locus
Plasma membrane
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant full-length human GYPA protein
Target Antigen
CD235a | Glycophorin-A
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
GYPA/3219R
Conjugation
CF405S
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Positive Control
Erythrocytes in any human tissues
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
39 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7649290/datasheet/bnc043219-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7649290/msds/bnc043219-100.pdf
CAS Number
9007-83-4
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