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Anti-Glycophorin A / CD235a (Erythrocyte Marker)(GYPA/3219R), CF405S conjugate

Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

GYPA

Gene ID

2993 & 2994

NCBI Gene ID

434973; 654368

UniProt

P02724

Cellular Locus

Plasma membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant full-length human GYPA protein

Target Antigen

CD235a | Glycophorin-A

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

GYPA/3219R

Conjugation

CF405S

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Positive Control

Erythrocytes in any human tissues

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

39 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7649290/datasheet/bnc043219-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7649290/msds/bnc043219-100.pdf

CAS Number

9007-83-4

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