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Anti-CD79b (B-Cell Marker)(B29/123)

CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

AGM6; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; IGB; Immunoglobulin-associated B29 protein

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD79B

Gene ID

974

NCBI Gene ID

89575

UniProt

P40259

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Human

Immunogen

Synthetic peptide representing the c-terminus from residue 215 of the murine B29 polypeptide.

Target Antigen

CD79b

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

B29/123

Conjugation

Purified, with BSA

Disease

Tumor

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Positive Control

Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

39 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7648385/datasheet/bnub3107-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7648385/msds/bnub3107-500.pdf

CAS Number

9007-83-4

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