Anti-CD29 (Stem Cell Marker)(12G10), CF568 conjugate
Recognizes CD29. Binds to the cell membrane of T- and B- lymphocytes, monocytes, platelets, fibroblasts, endothelial cells, mast cells and smooth muscle cells. CD29 is an adhesion receptor and co-stimulatory molecule. This antigen was initially characterized as GPIIa on platelets and as the common b1 subunit of the very late antigen (VLA) protein family. CD29 forms a non-covalent heterodimeric complex with integrin alpha subunits. It also mediates adhesion to invasion and thrombospondin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ITGB1
Gene ID
3688
NCBI Gene ID
643813
UniProt
P05556
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Purified human beta 1 integrin from HT1080 fibrosarcoma cell extract.
Target Antigen
CD29
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
12G10
Conjugation
CF568
Source
Animal
Applications
Flow, surface (published) | Functional studies (published) | IF (published) | IP (published)
Validated Applications
FC,IF,IP
Positive Control
HT1080 whole cell lysate. HeLa cell line.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
110 kDa (non-reduced) & 130 kDa (reduced)
Additionnal Information
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7646549/datasheet/bnc682905-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7646549/msds/bnc682905-100.pdf
CAS Number
9007-83-4
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