Anti-Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2713), Biotin conjugate
Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Carboxypeptidase A1; CPA1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CPA1
Gene ID
1357
NCBI Gene ID
2879
UniProt
P15085
Cellular Locus
Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant full-length human CPA1 protein
Target Antigen
Carboxypeptidase A1
Clonality
Monoclonal
Isotype
IgG κ
Clone
CPA1/2713
Conjugation
Biotin
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Field of Research
Endocrinology
Positive Control
Pancreas
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
47 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7644497/datasheet/bncb2713-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7644497/msds/bncb2713-500.pdf
CAS Number
9007-83-4
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