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Anti-Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker)(CPA1/2713), Biotin conjugate

Carboxypeptidase A1 (CPA1) is a secreted zinc metalloprotease that is highly expressed in pancreatic tissue. It catalyzes the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Carboxypeptidase A1; CPA1

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CPA1

Gene ID

1357

NCBI Gene ID

2879

UniProt

P15085

Cellular Locus

Secreted (extracellular)

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full-length human CPA1 protein

Target Antigen

Carboxypeptidase A1

Clonality

Monoclonal

Isotype

IgG κ

Clone

CPA1/2713

Conjugation

Biotin

Disease

Tumor

Source

Animal

Applications

IHC, FFPE (verified) | WB (verified)

Validated Applications

IHC,FFPE,WB

Field of Research

Endocrinology

Positive Control

Pancreas

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

47 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7644497/datasheet/bncb2713-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7644497/msds/bncb2713-500.pdf

CAS Number

9007-83-4

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