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Anti-S100A2 / S100 Calcium Binding Protein A2(CPTC-S100A2-2)

S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

CAN19; MGC111539; S100L

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

S100A2

Gene ID

6273

NCBI Gene ID

516484

UniProt

P29034

Cellular Locus

Nucleus & cytoplasm

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full-length human S100A2 protein

Target Antigen

S100 Calcium Binding Protein A2 | S100A2

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CPTC-S100A2-2

Conjugation

Purified, with BSA

Source

Animal

Applications

Flow, intracellular (verified) | IF (verified) | IHC, FFPE (verified) | WB (verified)

Validated Applications

FC,IF,IHC,FFPE,WB

Positive Control

HeLa. A549, HACAT, BxPC3 and A431 cell lysates; Skin and squamous cell cervical carcinoma.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

11.12 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7643252/datasheet/bnub2591-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7643252/msds/bnub2591-500.pdf

CAS Number

9007-83-4

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