Anti-S100A2 / S100 Calcium Binding Protein A2(CPTC-S100A2-2)
S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
CAN19; MGC111539; S100L
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
S100A2
Gene ID
6273
NCBI Gene ID
516484
UniProt
P29034
Cellular Locus
Nucleus & cytoplasm
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant full-length human S100A2 protein
Target Antigen
S100 Calcium Binding Protein A2 | S100A2
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CPTC-S100A2-2
Conjugation
Purified, with BSA
Source
Animal
Applications
Flow, intracellular (verified) | IF (verified) | IHC, FFPE (verified) | WB (verified)
Validated Applications
FC,IF,IHC,FFPE,WB
Positive Control
HeLa. A549, HACAT, BxPC3 and A431 cell lysates; Skin and squamous cell cervical carcinoma.
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
11.12 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7643252/datasheet/bnub2591-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7643252/msds/bnub2591-500.pdf
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items