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Anti-EZH2 / KMT6(EZH2/2536)

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Enhancer of zeste 2 polycomb repressive complex 2 subunit; Enhancer of zeste homolog 2 (EZH2); ENX1; Enx1h; EZH2b; Histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; Lysine N-methyltransferase 6; WVS; WVS2

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

EZH2

Gene ID

2146

NCBI Gene ID

444082

UniProt

Q15910

Cellular Locus

Nucleus

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant full-length human EZH2 protein

Target Antigen

EZH2 | KMT6

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

EZH2/2536

Conjugation

Purified, with BSA

Source

Animal

Applications

WB (verified)

Validated Applications

WB

Positive Control

MCF7, HeLa, U-2 OS or HEK-293 whole cell lysates. Human tonsil, testis or prostate tissue.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

81-102 kDa

Additionnal Information

Western blot 0.5-1.0 ug/mL; Optimal dilution for a specific application should be determined.

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7642776/datasheet/bnub2536-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7642776/msds/bnub2536-100.pdf

CAS Number

9007-83-4

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