Anti-FOLH1 / PSMA (Prostate Epithelial Marker)(FOLH1/2363), CF640R conjugate
Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FOLH1
Gene ID
2346
NCBI Gene ID
654487
UniProt
Q04609
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human FOLH1 protein fragment (around aa 232-433) (exact sequence is proprietary)
Target Antigen
FOLH1 | PSMA
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
FOLH1/2363
Conjugation
CF640R
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Positive Control
LNCap or HepG2 cells. Prostate Carcinoma.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7641154/datasheet/bnc402363-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7641154/msds/bnc402363-100.pdf
CAS Number
9007-83-4
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