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Anti-Lactoylglutathione Lyase(CPTC-GLO1-1)

GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

Aldoketomutase; epididymis secretory protein Li 74; Glo1; Glx I; glyoxalase 1 complex; glyoxalase 1 regulatory; glyoxalase 1 structural; glyoxalase domain containing 1; Glyoxalase I; glyoxylase 1; Ketone-aldehyde mutase; lactoyl glutathione lyase; Lactoylglutathione lyase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

GLO1

Gene ID

2739

NCBI Gene ID

268849

UniProt

Q04760

Cellular Locus

Cytoplasmic

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant human full-length GLO1 protein

Target Antigen

Lactoylglutathione Lyase

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

CPTC-GLO1-1

Conjugation

Purified, with BSA

Disease

Tumor

Source

Animal

Applications

IHC, FFPE (verified) | WB (verified)

Validated Applications

IHC,FFPE,WB

Positive Control

A431, HepG2, MOLT and Raji cell lysates. Ovarian carcinoma or prostate carcinoma.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

24-26 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7640027/datasheet/bnub2258-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7640027/msds/bnub2258-500.pdf

CAS Number

9007-83-4

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