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Anti-Glucose 6-Phosphate Isomerase(CPTC-GPI-1)

Besides its role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_

Product Specifications

Synonyms

AMF; aurocrine motility factor; EC 5.2.1.9; GNPI; Gpi1; hexose monophosphate isomerase; neuroleukin; NLK; oxoisomerase; PGI; PHI; phosphoglucose isomerase; phosphosaccharomutase; SA-36; sperm antigen 36

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

GPI

Gene ID

2821

NCBI Gene ID

466471

UniProt

P06744

Cellular Locus

Cytoplasmic|Secreted (extracellular)

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant human full-length GPI protein

Target Antigen

Glucose 6-Phosphate Isomerase

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

CPTC-GPI-1

Conjugation

Purified, with BSA

Source

Animal

Applications

IF (verified) | IHC, FFPE (verified) | WB (verified)

Validated Applications

IF,IHC,FFPE,WB

Positive Control

T47D, PC3, MCF-7, HepG2 and A549 cells. Brain, pancreas or thyroid carcinoma.

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

55 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7639978/datasheet/bnub2257-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7639978/msds/bnub2257-500.pdf

CAS Number

9007-83-4

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