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Anti-Cytochrome p450(M12P4H2), Biotin conjugate

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

4-nitrophenol 2-hydroxylase; CPE1; CYP2Ecytochrome P450 2E1; CYPIIE1; cytochrome P450; family 2; subfamily E; polypeptide 1; cytochrome P450; subfamily IIE (ethanol-inducible); polypeptide 1 ; Cytochrome P450-J; EC 1.14.13; EC 1.14.13.n7; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450C2E; P450-J; xenobiotic monooxygenase

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CYP2E1

Gene ID

1571

NCBI Gene ID

12907

UniProt

P05181

Cellular Locus

Endoplasmic reticulum|Microsomes

Host

Mouse

Species Reactivity

Human

Immunogen

Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)

Target Antigen

Cytochrome p450

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

M12P4H2

Conjugation

Biotin

Source

Animal

Applications

IHC, FFPE (verified)

Validated Applications

IHC,FFPE

Positive Control

HepG2 cells. Liver.

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

~50-55 kDa

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7639209/datasheet/bncb2199-500.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7639209/msds/bncb2199-500.pdf

CAS Number

9007-83-4

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