Anti-Cytochrome p450(M12P4H2), Biotin conjugate
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CYP2E1
Gene ID
1571
NCBI Gene ID
12907
UniProt
P05181
Cellular Locus
Endoplasmic reticulum|Microsomes
Host
Mouse
Species Reactivity
Human
Immunogen
Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
Target Antigen
Cytochrome p450
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
M12P4H2
Conjugation
Biotin
Source
Animal
Applications
IHC, FFPE (verified)
Validated Applications
IHC,FFPE
Positive Control
HepG2 cells. Liver.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~50-55 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7639209/datasheet/bncb2199-500.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7639209/msds/bncb2199-500.pdf
CAS Number
9007-83-4
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