Anti-TCL1 (T-Cell Marker)(TCL1/2079), CF488A conjugate
T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32. 13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TCL1A
Gene ID
10232
NCBI Gene ID
2484
UniProt
P56279
Cellular Locus
Nucleus & cytoplasm
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant fragment (around aa 2-109) of human TCL1 protein (exact sequence is proprietary)
Target Antigen
TCL1
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
TCL1/2079
Conjugation
CF488A
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Positive Control
Ramos or Raji cells. Tonsil or T-cell Lymphoma.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
14 kDa
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7637690/datasheet/bnc882079-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7637690/msds/bnc882079-100.pdf
CAS Number
9007-83-4
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