Anti-CD3e, Mouse(145-2C11), CF640R conjugate
CD3 chains. CD3 plays a critical role in TCR signal transduction, T-cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful for in vitro blocking and activation assays, as well as apoptosis induction and in vivo T-cell depletion._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Cd3e (Mouse)
Gene ID
12501
NCBI Gene ID
210361
UniProt
P22646
Cellular Locus
Plasma membrane
Host
Armenian Hamster
Species Reactivity
Mouse
Immunogen
H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37
Target Antigen
CD3e
Clonality
Monoclonal
Isotype
IgG κ
Clone
145-2C11
Conjugation
CF640R
Disease
Tumor
Source
Animal
Applications
Flow, surface (published) | Functional studies (published) | IP (published)
Validated Applications
FC,IP,Functional assays
Positive Control
MPBMC's or Thymus or Lymph Node.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
23 kDa
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7637205/datasheet/bnc402013-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7637205/msds/bnc402013-100.pdf
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items