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Anti-IL-4 (Interleukin-4), Mouse(11B11), CF405S conjugate

IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

B cell growth factor 1 (BCGF1); B cell IgG differentiation factor; B-Cell Stimulatory Factor 1 (BSF1); Binetrakin; IGG1 induction factor; IL4; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene ID

16189

NCBI Gene ID

276360

UniProt

P07750

Cellular Locus

Secreted (extracellular)

Host

Rat

Species Reactivity

Mouse

Immunogen

Partially Purified native Mouse IL-4

Target Antigen

IL-4 ,

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

11B11

Conjugation

CF405S

Source

Animal

Applications

Flow, intracellular (published) | Functional studies (published) | ELISA (published)

Validated Applications

FC,ELISA

Positive Control

Spleen, Thymus or Lymph Node.

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

13-14 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1992) 89:6065-6069. (functional studies; ELISA) J Immunol (2005) 174:1063-1072. (ELISA, Flow)

Shipping Conditions

Room temperature

Storage Conditions

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7637127/datasheet/bnc042008-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7637127/msds/bnc042008-100.pdf

CAS Number

9007-83-4

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