Anti-CD8b, Mouse(H35-17.2), CF488A conjugate
This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Cd8b1 (Mouse)
Gene ID
12526
NCBI Gene ID
3331
UniProt
P10300
Cellular Locus
Plasma membrane
Host
Rat
Species Reactivity
Mouse
Immunogen
Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c
Target Antigen
CD8b,
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
H35-17.2
Conjugation
CF488A
Source
Animal
Applications
Flow, surface (published) | Functional studies (published)
Validated Applications
FC,Functional assays
Positive Control
MPBMC's or Thymus.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
37 kDa
References & Citations
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7637067/datasheet/bnc882003-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7637067/msds/bnc882003-100.pdf
CAS Number
9007-83-4
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