Anti-Bcl-X (Apoptosis Marker)(BCL2L1/1762), CF405S conjugate
Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes apoptosis. This MAb reacts with both Bcl-XS and Bcl-XL proteins, and shows no cross-reaction with Bcl-2 or Bax proteins.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
Bcl-x; Bcl-2-like protein 1; BCL2L1; Apoptosis regulator Bcl-X
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BCL2L1
Gene ID
598
NCBI Gene ID
516966
UniProt
Q07817
Cellular Locus
Cytoplasmic|Endoplasmic reticulum|Mitochondria
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant human BCL2L1 protein fragment (around aa 1-135) (exact sequence is proprietary)
Target Antigen
Bcl-x
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
BCL2L1/1762
Conjugation
CF405S
Source
Animal
Field of Research
Apoptosis, Cancer
Positive Control
Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
27 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7634058/datasheet/bnc041762-100.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7634058/msds/bnc041762-100.pdf
CAS Number
9007-83-4
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