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Anti-CD8B (Cytotoxic / Suppressor T-Cell Marker)(CBB/1595)

The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

Synonyms

CD8 antigen 37kDa chain; CD8 antigen; beta chain; CD8 antigen; beta polypeptide 1 (p37); CD8 antigen; beta polypeptide 1; CD8B; LEU2; LYT3; OX 8 membrane antigen; p37; T cell surface glycoprotein CD8 beta chain

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CD8B

Gene ID

926

NCBI Gene ID

405667

UniProt

P10966

Cellular Locus

Plasma membrane

Host

Mouse

Species Reactivity

Bovine,Goat,Sheep

Immunogen

Antibody was raised against bovine CD8b.

Target Antigen

CD8b,

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

CBB/1595

Conjugation

Purified, with BSA

Source

Animal

Positive Control

HuT78 or hPBL. Tonsil

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

32 kDa

Additionnal Information

For coating for ELISA, order Ab without BSA|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Optimal dilution and staining procedure for a specific application should be determined by user|Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry

Shipping Conditions

Room temperature

Storage Conditions

4°C; Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

2 years

Product Datasheet

https://cdn.gentaur.com/products/37/7632124/datasheet/bnub1595-100.pdf

Product MSDS

https://cdn.gentaur.com/products/37/7632124/msds/bnub1595-100.pdf

CAS Number

9007-83-4

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