Anti-BTLA(BTLA/1528)
B and T lymphocyte attenuator (BTLA) is a member of the CD28 Ig superfamily of inhibitory co-receptors, along with CTLA-4 and PD-1. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family receptors. Rather, it is engaged by herpesvirus entry mediator (HVEM), a member of the TNF receptor superfamily, leading to an inhibited immune response. It also plays a role in immune tolerance. BTLA is expressed on most CD4 and CD8 T cells, B cells, macrophages, dentritic cells, and NK cell. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product Specifications
Synonyms
BTLA; B and T lymphocyte associated protein; B and T lymphocyte attenuator; CD272
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BTLA
Gene ID
151888
NCBI Gene ID
445162
UniProt
Q7Z69
Cellular Locus
Plasma membrane
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant full-length human BTLA protein
Target Antigen
BTLA | CD272
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
BTLA/1528
Conjugation
Purified, BSA-free
Source
Animal
Field of Research
Immunology
Positive Control
Human lymph node or MDAMB468 xenograft.
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
33 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/7631091/datasheet/bnum1528-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/7631091/msds/bnum1528-50.pdf
CAS Number
9007-83-4
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