Ciprofibrate

Ciprofibrate (Win35833) is a potent peroxisome proliferator and increases the phosphorylation level of the PPARalpha[1]. Ciprofibrate acts as an orally active hypolipidaemic agent and can be used for the research of primary hyperlipidaemias[2].

Product Specifications

CAS Number

[52214-84-3]

Product Name Alternative

Win35833

UNSPSC

12352005

Hazard Statement

H350

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Ciprofibrate.html

Concentration

10mM

Purity

99.93

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(C)(OC1=CC=C(C2C(Cl)(Cl)C2)C=C1)C(O)=O

Molecular Formula

C13H14Cl2O3

Molecular Weight

289.15

Precautions

H350

References & Citations

[1]Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58 (6) : p. 1001-8.|[2]Agnes M Rimando, et al. Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem. 2005 May 4;53 (9) :3403-7.|[3]Thing-Fong Tzeng, et al. 6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism. Nutrients. 2015 Feb 4;7 (2) :999-1020.