Nifurtimox
Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH) .
Product Specifications
CAS Number
[23256-30-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Lactate Dehydrogenase; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Nifurtimox.html
Purity
99.72
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=S1(CC(C)N(/N=C/C2=CC=C([N+]([O-])=O)O2)CC1)=O
Molecular Formula
C10H13N3O5S
Molecular Weight
287.30
Precautions
H315, H319, H320
References & Citations
[1]Cabanillas Stanchi KM, et al. Nifurtimox reduces N-Myc expression and aerobic glycolysis in neuroblastoma. Cancer Biol Ther. 2015;16 (9) :1353-63.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Trypanosoma
Available Sizes
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