Isozaluzanin C
Product Specifications
UNSPSC Description
Isozaluzanin C (Dehydrozaluzanin c-derivative) is an anti-inflammatory agent that can be isolated from Saussurea lappa and has immunomodulatory effects. Isozaluzanin C improves tissue damage (lung, kidney, and liver) and excessive inflammation in mice induced by LPS (HY-D1056) or CRKP infection. Isozaluzanin C can be used in the study of bacterial infections and sepsi[1][2].
Target Antigen
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isozaluzanin-c.html
Solubility
10 mM in DMSO
Smiles
O=C(O[C@@]([C@@]1([H])C([C@H](O)C[C@@]21[H])=C)([H])[C@@]3([H])CCC2=C)C3=C
Molecular Weight
246.30
References & Citations
[1]Kalsi S,et al. Isodehydrocostus lactone and isozaluzanin C, two guaianolides from Saussurea lappa[J]. Phytochemistry, 1983, 22(9): 1993-1995.|[2]Zou, et al. Dehydrozaluzanin C-derivative protects septic mice by alleviating over-activated inflammatory response and promotes the phagocytosis of macrophages[J]. bioRxiv, 2023: 2023.11. 01.565192.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7741/Isozaluzanin-C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7741/
Clinical Information
No Development Reported
CAS Number
67667-64-5
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