Isoflurane

Isoflurane is a volatile general anaesthetic used for induction and maintenance of general anesthesia. Isoflurane binds to and enhances GABAA receptor. Isoflurane inhibits electron transfer in respiratory complex I[1][2].

Product Specifications

CAS Number

[26675-46-7]

UNSPSC

12352211

Hazard Statement

H336, H373

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isoflurane.html

Purity

99.27

Smiles

FC(F)(F)C(Cl)OC(F)F

Molecular Formula

C3H2ClF5O

Molecular Weight

184.49

Precautions

H336, H373

References & Citations

[1]Enrique Rodriguez, et al. Anaesthetics disrupt complex I-linked respiration and reverse the ATP synthase. Biochim Biophys Acta Bioenerg. 2025 Jan 1;1866 (1) :149511. |[2]A Jenkins, et al. Effects of temperature and volatile anesthetics on GABA (A) receptors. Anesthesiology. 1999 Feb;90 (2) :484-91.