CVT-5440
Product Specifications
UNSPSC Description
CVT-5440 is a xanthine based, selective, high affinity A2B adenosine receptors (AdoR) antagonist with a Ki of 50 nM (selectivity A1> 200; A2A>200; A3>167). CVT-5440 has the potential for asthma research[1].
Target Antigen
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cvt-5440.html
Smiles
O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=C(OCC4=NOC(C5=CC=CC(OC)=C5)=N4)C=C3)N2)C1=O
Molecular Weight
516.55
References & Citations
[1]Jeff Zablocki, et al. The discovery of a selective, high affinity A(2B) adenosine receptor antagonist for the potential treatment of asthma.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123038/CVT-5440-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123038/
Clinical Information
No Development Reported
CAS Number
531506-64-6
Curated Selection
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