(E)-2-Hydroxycinnamaldehyde
Product Specifications
UNSPSC Description
(E)-2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E)-2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E)-2-Hydroxycinnamaldehyde has antitumor activity[1].
Target Antigen
Apoptosis; Reactive Oxygen Species; STAT
Type
Natural Products
Related Pathways
Apoptosis;Immunology/Inflammation;JAK/STAT Signaling;Metabolic Enzyme/Protease;NF-κB;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-2-hydroxycinnamaldehyde.html
Solubility
10 mM in DMSO
Smiles
O=C/C=C/C1=C(C=CC=C1)O
Molecular Weight
148.16
References & Citations
[1]Yoon YJ, et al. 2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation. Cancer Sci. 2019 Jan;110(1):366-378.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3149/E-2-Hydroxycinnamaldehyde-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3149/
Clinical Information
No Development Reported
CAS Number
60125-23-7
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