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C14 Ceramide (d18:1/14:0)

Product Specifications

UNSPSC Description

C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research[1][2].

Target Antigen

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/c14-ceramide-d18-1-14-0.html

Smiles

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(CCCCCCCCCCCCC)=O

Molecular Weight

509.85

References & Citations

[1]Oertel S, et al. Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity. Cell Mol Life Sci. 2017 Aug;74(16):3039-3055.|[2]Choi S, et al. Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells. FASEB J. 2018 Oct;32(10):5724-5736.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-124177A/C14-Ceramide-d18-1-14-0-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-124177A/

Clinical Information

No Development Reported

CAS Number

123408-74-2

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