11β-HSD1-IN-14
Product Specifications
UNSPSC Description
11β-HSD1-IN-14 (Compound 17) is a selective inhibitor for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1), with IC50 of 74 nM for human HSD1, and 603 nM for HSD1 expressed HEK293 cell[1].
Target Antigen
11β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/11β-hsd1-in-14.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C2=CC=CC=C2)C=C1)(N3CCN(CC3)C4=NC=CC=C4C(F)(F)F)=O
Molecular Weight
447.47
References & Citations
[1]Sun D, et al., Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1). Bioorg Med Chem Lett. 2008 Jun 15;18(12):3513-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162026/11β-HSD1-IN-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162026/
Clinical Information
No Development Reported
CAS Number
946394-50-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![M-CSF (CSF1) Mouse Monoclonal Antibody [Clone 1D10]](https://cdn.genprice.uk/genprice/genprice4.png)