CD45, Human (Biotinylated, HEK293, His-Avi)

Receptor-type tyrosine-protein phosphatase C (PTPRC) is a receptor type PTP and an essential positive regulator of T- and B-cell antigen receptor signaling. PTPRC functions through direct interaction with antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. PTPRC also suppresses JAK kinases as a regulator of cytokine receptor signaling. CD45 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD45 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of CD45 Protein, Human (Biotinylated, HEK293, His-Avi) is 391 a.a., with molecular weight of 80-110 kDa.

QSPTPSPTDA YLNASETTTL SPSGSAVIST TTIATTPSKP TCDEKYANIT VDYLYNKETK LFTAKLNVNE NVECGNNTCT NNEVHNLTEC KNASVSISHN SCTAPDKTLI LDVPPGVEKF QLHDCTQVEK ADTTICLKWK NIETFTCDTQ NITYRFQCGN MIFDNKEIKL ENLEPEHEYK CDSEILYNNH KFTNASKIIK TDFGSPGEPQ IIFCRSEAAH QGVITWNPPQ RSFHNFTLCY IKETEKDCLN LDKNLIKYDL QNLKPYTKYV LSLHAYIIAK VQRNGSAAMC HFTTKSAPPS QVWNMTVSMT SDNSMHVKCR PPRDRNGPHE RYHLEVEAGN TLVRNESHKN CDFRVKDLQY STDYTFKAYF HNGDYPGEPF ILHHSTSYNS K