Cefditoren

Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC50 of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections[1][2][3].

Product Specifications

CAS Number

[104145-95-1]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefditoren.html

Purity

98.14

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C1=C(/C=C\C2=C(N=CS2)C)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)([H])N1C3=O)=O

Molecular Formula

C19H18N6O5S3

Molecular Weight

506.58

References & Citations

[1]Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD) : National Institute of Child Health and Human Development; 2006–. Cefditoren. 2023 Aug 15.|[2]Giuliano S, et al. Cefditoren: a clinical overview. New Microbiol. 2023 Feb;46 (1) :9-17.|[3]Sempere J, et al. A national longitudinal study evaluating the activity of cefditoren and other antibiotics against non-susceptible Streptococcus pneumoniae strains during the period 2004-20 in Spain. J Antimicrob Chemother. 2022 Mar 31;77 (4) :1045-1051.