MTT5
Product Specifications
UNSPSC Description
MTT5 is a toll-like receptor 7 (TLR7) agonist. MTT5 can couple with Deruxtecan (HY-13631E) and exert anti-tumor activity in HER2 positive solid tumors through tumor cell killing and immune activation[1].
Target Antigen
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mtt5.html
Smiles
COCCOC1=NC(N)=C2NC(N(C2=N1)CC3=CC=C(C=C3)C(N4CC5CNCC5C4)=O)=O
Molecular Weight
453.49
References & Citations
[1]Yue H, et al. A DXd/TLR7-agonist dual-conjugate anti-HER2 ADC exerts robust anti-tumor activity through tumor cell killing and immune activation. Mol Cancer Ther. 2024 Jul 31.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169017/MTT5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169017/
Clinical Information
No Development Reported
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