ONO-AE 248
Product Specifications
UNSPSC Description
ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ono-ae-248.html
Smiles
CCCCC[C@H](OC)/C=C/[C@@H]1[C@H](C(C[C@H]1OC)=O)C/C=C\CCCC(O)=O
Molecular Weight
380.52
References & Citations
[1]Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12184/ONO-AE-248-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12184/
Clinical Information
No Development Reported
CAS Number
211230-67-0
Curated Selection
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