3F8
3F8 is a potent and selective GSK-3β inhibitor that could be useful as new reagent and potential therapeutic candidate for GSK3 related diseases[1].
Product Specifications
CAS Number
[159109-11-2]
UNSPSC
12352005
Hazard Statement
H302
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/3f8.html
Solubility
10 mM in DMSO
Smiles
O=C(N1)C2=C3C(C=C(OC)C(OC)=C3)=C(CC)N=C2C1=O
Molecular Formula
C15H14N2O4
Molecular Weight
286.28
Precautions
P264-P270-P330-P501
References & Citations
[1]Zhong H, et al. Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Mol Biosyst. 2009 Nov;5 (11) :1356-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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