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Myokinasib-II

Myokinasib-II is a myosin light chain kinase (MLCK) inhibitor, which is a potential target for inflammatory diseases, cancer and other diseases.[1].

Product Specifications

UNSPSC

12352005

Target

Myosin

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/myokinasib-ii.html

Smiles

O=C(C1(C(C2=CC=C(F)C=C2C)C([N+]([O-])=O)C3(C)N1)CC4=C3NC5=C4C=CC=C5)OCC

Molecular Formula

C24H24FN3O4

Molecular Weight

437.46

References & Citations

[1]Kumar G, et al. Identification and Benchmarking of Myokinasib-II as a Selective and Potent Chemical Probe for Exploring MLCK1 Inhibition. ACS Chem Biol. 2024 Oct 18;19 (10) :2165-2175.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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