PLY, Streptococcus pneumoniae serotype 4 (Baculovirus, His-Myc)

The PLY protein, a cholesterol-dependent toxin, induces cytolysis by forming pores in host membranes with a significant conformational change and oligomeric pore complex formation. Cholesterol is crucial for binding, insertion, and pore formation. PLY Protein, Streptococcus pneumoniae serotype 4 (Baculovirus, His-Myc) is the recombinant PLY protein, expressed by Sf9 insect cells , with N-10*His, C-Myc labeled tag. The total length of PLY Protein, Streptococcus pneumoniae serotype 4 (Baculovirus, His-Myc) is 470 a.a., with molecular weight of ~56.8 kDa.

ANKAVNDFIL AMNYDKKKLL THQGESIENR FIKEGNQLPD EFVVIERKKR SLSTNTSDIS VTATNDSRLY PGALLVVDET LLENNPTLLA VDRAPMTYSI DLPGLASSDS FLQVEDPSNS SVRGAVNDLL AKWHQDYGQV NNVPARMQYE KITAHSMEQL KVKFGSDFEK TGNSLDIDFN SVHSGEKQIQ IVNFKQIYYT VSVDAVKNPG DVFQDTVTVE DLKQRGISAE RPLVYISSVA YGRQVYLKLE TTSKSDEVEA AFEALIKGVK VAPQTEWKQI LDNTEVKAVI LGGDPSSGAR VVTGKVDMVE DLIQEGSRFT ADHPGLPISY TTSFLRDNVV ATFQNSTDYV ETKVTAYRNG DLLLDHSGAY VAQYYITWNE LSYDHQGKEV LTPKAWDRNG QDLTAHFTTS IPLKGNVRNL SVKIRECTGL AWEWWRTVYE KTDLPLVRKR TISIWGTTLY PQVEDKVEND