T638
T638 is a topoisomerase II (TOP2) inhibitor. T638 inhibits TOP2A activity with a IC50 of 0.7 uM. T638 strongly inhibits cancer cell growth[1].
Product Specifications
CAS Number
[2770585-67-4]
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t638.html
Purity
98.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CNC1=S)NC2=CC=C(NC3=CC=CC=C3)C=C2N
Molecular Formula
C18H16N4OS
Molecular Weight
336.41
References & Citations
[1]Matias-Barrios VM, et al. Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy. Cancers (Basel) . 2021 Jul 22;13 (15) :3675.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
