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Linalool-d3

Product Specifications

UNSPSC Description

Linalool-d3 is the deuterium labeled Linalool[1]. Linalool is natural monoterpene in essential olis of coriander, acts as a competitive antagonist of Nmethyl d-aspartate (NMDA) receptor, with anti-tumor, anti-cardiotoxicity activity[2].Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[3].

Target Antigen

Apoptosis; Endogenous Metabolite; iGluR

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Purity

95.17

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C/C(C)=C\CCC(C)(O)/C([2H])=C([2H])/[2H]

Molecular Weight

157.27

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Oner Z1, et al. The protective and therapeutic effects of linalool against doxorubicin-induced cardiotoxicity in Wistar albino rats. Hum Exp Toxicol. 2019 Apr 12:960327119842634.|[3]Jun HJ, et al. Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome. J Lipid Res. 2014 Jun55(6):1098-110.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Clinical Information

No Development Reported

CAS Number

1216673-02-7

Available Sizes

Curated Selection

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