Lenalidomide-C5-acid
Lenalidomide-C5-acid is the Lenalidomide-based E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Lenalidomide-C5-acid can be used to synthesize PROTACs[1].
Product Specifications
CAS Number
[2338824-30-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenalidomide-c5-acid.html
Purity
96.36
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCNC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O)O
Molecular Formula
C19H23N3O5
Molecular Weight
373.40
References & Citations
[1]Krönke J, et al. Lenalidomide induces degradation of IKZF1 and IKZF3. Oncoimmunology. 2014 Jul 3;3 (7) :e941742.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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