TAAR1 agonist 1
Product Specifications
UNSPSC Description
TAAR1 agonist 1 (compound 6E) is a potent TAAR1 agonist with a potent TAAR1-Gs/Gq dual-pathway activation property. TAAR1 agonist 1 significantly alleviates MK-801-induced schizophrenia-like cognitive phenotypes[1].
Target Antigen
Trace Amine-associated Receptor (TAAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/taar1-agonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C2=CC=CO2)C=C1)[C@H](N)C
Molecular Weight
230.26
References & Citations
[1]Zhenzhen Zhou, et al. Structure-Based Design of Novel G-Protein-Coupled Receptor TAAR1 Agonists as Potential Antipsychotic Drug Candidates. J Med Chem. 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157955/TAAR1-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157955/
Clinical Information
No Development Reported
Curated Selection
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