Diheptanoyl Thio-PC
Product Specifications
UNSPSC Description
Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diheptanoyl-thio-pc.html
Smiles
C[N+](C)(C)CCOP(OC[C@H](SC(CCCCCC)=O)CSC(CCCCCC)=O)([O-])=O
Molecular Weight
513.69
References & Citations
[1]Hendrickson, et al. Chiral synthesis of a dithiolester analog of phosphatidylcholine as a substrate for the assay of phospholipase A2. J. Lipid Res. 24(11), 1532-1537 (1983).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W713925/Diheptanoyl-Thio-PC-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W713925/
Clinical Information
No Development Reported
CAS Number
89019-63-6
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