Schisandrin A
Schisandrin A inhibits CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respectively.
Product Specifications
CAS Number
[61281-38-7]
Product Name Alternative
Schizandrin-A; Wuweizisu-A; Deoxyschizandrin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; Cytochrome P450; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Schisandrin-A.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@H]1CC2=CC(OC)=C(OC)C(OC)=C2C3=C(OC)C(OC)=C(OC)C=C3C[C@H]1C
Molecular Formula
C24H32O6
Molecular Weight
416.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Li WL, et al. Inhibitory effects of Schisandrin A and Schisandrin B on CYP3A activity. Methods Find Exp Clin Pharmacol. 2010 Apr;32 (3) :163-9.|[2]Li WL, et al. Inhibitory effects of continuous ingestion of Schisandrin A on CYP3A in the rat. Basic Clin Pharmacol Toxicol. 2012 Feb;110 (2) :187-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP3
Available Sizes
Curated Selection
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